Gao-Hui Zhu, Jiayi Huang, Yang Bi, Yuxi Su, Yi Tang , Bai-Cheng He, Yun He, Jinyong Luo, Yi Wang, Liang Chen, Guo-Wei Zuo, Wei Jiang, Qing Luo, Jikun Shen, Bo Liu, Wen-Li Zhang, Qiong Shi, Bing-Qiang Zhang, Quan Kang, Jing Zhu, Jie Tian, Hue H. Luu, Rex C. Haydon, Yuan Chen, and Tong-Chuan He: (2009) Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells. Differentiation [Proof].

Yang Bi^#, Jiayi Huang^#, Yun He, Gao-Hui Zhu, Yuxi Su, Bai-Cheng He, Jinyong Luo, Yi Wang, Quan Kang, Qing Luo, Liang Chen, Guo-Wei Zuo, Wei Jiang, Bo Liu, Qiong Shi, Min Tang, Bing-Qiang Zhang, Yaguang Weng, Ailong Huang, Lan Zhou, Tao Feng, Hue H. Luu, Rex C. Haydon, Tong-Chuan He,* and Ni Tang* (2009) Wnt Antagonist SFRP3 Inhibits the Differentiation of Mouse Hepatic Progenitor Cells. Journal of Cellular Biochemistry [Proof] (# These authors contributed equally to the work; *corresponding authors).

Yuxi Su, Xiaoji Luo, Bai-Cheng He, Yi Wang, Liang Chen, Guo-Wei Zuo, Bo Liu, Yang Bi, Jiayi Huang, Gao-Hui Zhu, Yun He, Quan Kang, Jinyong Luo, Jikun Shen, Jin Chen, Xianqing Jing, Rex C. Haydon, Tong-Chuan He, and Hue H. Luu: (2009) Establishment and characterization of a new highly metastatic human osteosarcoma cell line.  Clinical & Experimental Metastasis  [Proof].

Ni Tang, Wen-Xin Song, Jinyong Luo, Xiaoji Luo, Jin Chen, Katie A.Sharff, Yang Bi, Bai-Cheng He, Jia-Yi Huang, Gao-Hui Zhu, Yu-Xi Su, Wei Jiang, Min Tang, Yun He, Yi Wang, Liang Chen, Guo-Wei Zuo, Jikun Shen, Xiaochuan Pan, Russell R. Reid, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He*: (2009) BMP9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/b-catenin signaling. Journal of Cellular and Molecular Medicine [Proof].

Katie A. Sharff*, Wen-Xin Song*, Xiaoji Luo, Ni Tang, Jinyong Luo, Jin Chen, Yang Bi, Bai-Cheng He, Jiayi Huang, Xinmin Li, Wei Jiang, Gao-Hui Zhu, Yuxi Su, Yun He, Jikun Shen, Yi Wang, Liang Chen, Guo-Wei Zuo, Bo Liu, Xiaochuan Pan, Russell R. Reid, Hue H. Luu, Rex C. Haydon#, and Tong-Chuan He#: (2009) Hey1 Basic Helix-Loop-Helix (bHLH) Protein Plays an Important Role in Mediating BMP9 Induced Osteogenic Differentiation of Mesenchymal Progenitor Cells. Journal of Biological Chemistry 284(1):649-659 [PDF]. (*equal contributions; # co-corresponding authors).

Quan Kang*, Wen-Xin Song*, Qing Luo, Ni Tang, Jinyong Luo, Xiaoji Luo, Jin Chen, Yang Bi, Bai-Cheng He, Jong Kyung Park, Wei Jiang, Yi Tang, Jiayi Huang, Yuxi Su, Gao-Hui Zhu, Yun He, Hong Yin, Zhenming Hu, Yi Wang, Liang Chen, Guowei Zuo, Xiaochuan Pan, Jikun Shen, Tamara Vokes, Russell Reid, Rex C. Haydon, Hue H. Luu^#, and Tong-Chuan He^#: (2009) A Comprehensive Analysis of the Dual Roles of BMPs in Regulating Adipogenic and Osteogenic Differentiation of Mesenchymal Progenitor Cells.  Stem Cells and Development 18(4): 545-559 [PDF] (*equal contributions to the work; #co-corresponding authors). 

Xiaoji Luo*, Jin Chen*, Wen-Xin Song, Ni Tang, Jinyong Luo, Zhong-Liang Deng, Katie A. Sharff, Gary He, Yang Bi, Bai-Cheng He, Erwin Bennett, Jiayi Huang, Quan Kang, Wei Jiang, Yuxi Su, Gao-Hui Zhu, Hong Yin, Yun He, Yi Wang, Jeffrey S. Souris, Liang Chen, Guo-Wei Zuo, Anthony G. Montag, Russell Reid, Rex C. Haydon, Hue H. Luu,# and Tong-Chuan He#: (2008) Osteogenic BMPs promote tumor growth of human osteosarcomas that harbor differentiation defects.  Laboratory Investigation  88(12):1264-1277 [PDF]. (*equal contributions; # co-corresponding authors). 

Xiaoji Luo, Katie A Sharff, Jin Chen, Tong-Chuan He and Hue H. Luu: (2008) S100A6 Expression and Function in Human Osteosarcoma.  Clinical Orthopaedics and Related Research  466: 2060–2070 [PDF].

Chong-Zhi Wang, Han H. Aung, Bin Zhang, Shi Sun, Xiao-Li Li, Hui He, Jing-Tian Xie, Tong-Chuan He, Wei Du And Chun-Su Yuan: (2008) Chemopreventive Effects of Heat-processed Panax Quinquefolius Root on Human Breast Cancer Cells.  Anticancer Research  28: 2545-51 [PDF].

Ni Tang, Wen-Xin Song, Jinyong Luo, Rex C. Haydon and Tong-Chuan He: (2008) Osteosarcoma Development and Stem Cell Differentiation.  Clinical Orthopaedics and Related Research  466: 2114–2130 [PDF].

Xiaoji Luo, Chong-Zhi Wang, Jin Chen, Wen-Xin Song, Jinyong Luo, Ni Tang, Bai-Cheng He, Quan Kang, Yitao Wang, Wei Du, Tong-Chuan He*, and Chun-Su Yuan* (2008) Characterization of gene expression regulated by American ginseng and ginsenoside Rg3 in human colorectal cancer cells. International Journal of Oncology  32: 975-983. (*co-corresponding authors). [PDF].

Zhong-Liang Deng, Katie A. Sharff, Ni Tang, Wen-Xin Song, Jinyong Luo, Xiaoji Luo, Jin Chen, Erwin Bennett, Russell Reid, David Manning, Anita Xue, Anthony G. Montag, Hue H. Luu, Rex C. Haydon and Tong-Chuan He: (2008) Regulation of osteogenic differentiation during skeletal development. Frontiers in Bioscience 13: 2001-2021. [PDF].

Jinyong Luo, Zhong-Liang Deng, Xiaoji Luo, Ni Tang, Wen-Xin Song, Jin Chen, Katie A. Sharff, Hue H. Luu, Rex C. Haydon, Kenneth W. Kinzler, Bert Vogelstein, and Tong-Chuan He:  (2007) A protocol for rapid generation of recombinant adenoviruses using the AdEasy system.  Nature Protocols  2(5): 1236-1247 [PDF].

Qing Luo, Quan Kang, Wen-Xin Song, Hue H. Luu, Xiaoji Luo, Naili An, Jinyong Luo, Zhong-Liang Deng, Wei Jiang, Hong Yin, Jin Chen, Katie Sharff , Ni Tang, Erwin Bennett, Rex C. Haydon, and Tong-Chuan He:  (2007) Selection and validation of optimal siRNA target sites for RNAi-mediated gene silencing.  Gene  395(1-2): 160-169 [PDF].

Chong-Zhi Wang, Jing-Tian Xie, Bin Zhang, Ming Ni, Anna Fishbein, Han H. Aung, Sangeeta R. Mehendale, Wei Du, Tong-Chuan He, and Chun-Su Yuan: (2007) Chemopreventive effects of Panax notoginseng and its major constituents on SW480 human colorectal cancer cells.  International Journal of Oncology  31(5):1149-1156 [PDF].

Patrick Bolt, Neil Clerk, Hue H. Luu, Quan Kang, Jennifer L. Kummer, Zhong-Liang Deng, Kirstina Olson, Frank Primus, Anthony G. Montag, Tong-Chuan He, Rex C. Haydon, and Brian C. Toolan: (2007) BMP14 gene therapy increases tendon tensile strength in a rat model of Achilles tendon injury.  Journal of Bone and Joint Surgery (American)  89:1315-1320 [PDF].

Hue H. Luu, Wen-Xin Song, Xiaoji Luo, David Manning, Jinyong Luo, Zhongliang Deng, Katie Sharff, Anthony G. Montag, Rex C. Haydon, and Tong-Chuan He:  (2007) Distinct Roles of Bone Morphogenetic Proteins in Osteogenic Differentiation of Mesenchymal Stem Cells.   Journal of Orthopaedic Research  25(5): 665-677 [PDF].

Yu-Hua Tseng and Tong-Chuan He: (2007) Bone Morphogenetic Proteins and Adipocyte Differentiation.  Cellscience Reviews 3(3): 342-360 [PDF].

Jinyong Luo, Jin Chen, Zhong-Liang Deng, Xiaoji Luo, Wen-Xin Song, Katie Sharff, Ni Tang, Rex C. Haydon, Hue H. Luu, and Tong-Chuan He: (2007) Wnt signaling and human diseases: what are the therapeutic implications?   Laboratory Investigation   87(2): 97-103.  [PDF]

Rex C. Haydon, Hue H. Luu, and Tong-Chuan He: (2007) Osteosarcoma and Osteoblastic Differentiation:  A New Perspective on Oncogenesis.   Clinical Orthopaedics and Related Research   454: 237-246.  [PDF]

Chong-Zhi Wang, Bin Zhang, Wen-Xin Song, Anbao Wang, Ming Ni, Xiaoji Luo, Han H. Aung, Jing-Tian Xie, Robin Tong, Tong-Chuan He, and Chun-Su Yuan. (2006) Steamed American Ginseng Berry: Ginsenoside Analyses and Anticancer Activities.  Journal of Agriculture and Food Chemistry  54: 9936-9942.  [PDF]

Zhang BQ, Huang Y, Tang N, Wu Y, Zhang J, Chen WX, He TC, Huang AL. (2006) Inhibition of HBV replication and antigen expression by RNA interference against different targets.  Chinese Journal of Hepatology (Zhonghua Gan Zang Bing Za Zhi) 14 (9):662-5.

Wang CZ, Luo X, Zhang B, Song WX, Ni M, Mehendale S, Xie JT, Aung HH, He TC, Yuan CS. (2006) Notoginseng enhances anti-cancer effect of 5-fluorouracil on human colorectal cancer cells.  Cancer Chemother Pharmacol. 2006 Sep 29; [Epub ahead of print].  [PDF]

Weike Si, Quan Kang, Hue H. Luu, Jong Kyung Park, Qing Luo, Wen-Xin Song, Wei Jiang, Xiaoji Luo, Xinmin Li, Hong Yin, Anthony G. Montag, Rex C. Haydon, and Tong-Chuan He: (2006) CCN1/Cyr61 is regulated by canonical Wnt signal and plays an important role in Wnt3A-induced early osteogenic differentiation.  Molecular and Cellular Biology 26(8): 2955–2964.  [PDF]

Yejia Zhang, Howard S. An, Eugene J-M.A. Thonar, Susan Chubinskaya, Tong-Chuan He, and Frank M. Phillips. (2006) Comparative effects of bone morphogenetic proteins and sox9 overexpression on extracellular matrix metabolism of bovine nucleus pulposus cells.  Spine   31(19): 2173-9.  [PDF]

Hue H. Luu, Quan Kang, Jong Kyung Park, Weike Si, Qing Luo, Wei Jiang, Hong Yin, Anthony G. Montag, Michael A. Simon, Terrance D. Peabody, Rex C. Haydon, Carrie W. Rinker-Schaeffer, and Tong-Chuan He: (2005) An orthotopic model of human osteosarcoma growth and spontaneous pulmonary metastasis.  Clinical & Experimental Metastasis  22(4): 319-329. [PDF]

Hue H. Luu, Lan Zhou, Rex C. Haydon, Andrea T. Deyrup, Anthony G. Montag, Dezheng Huo, Robert Heck, Claus W. Heizmann, Terrance Peabody, Michael A. Simon, and Tong-Chuan He: (2005) Increased expression of S100A6 is associated with decreased metastasis and inhibition of cell migration and anchorage independent growth in human osteosarcoma.  Cancer Letters  229(1): 135-148. [PDF]

Frank M. Phillips, Patrick Bolt, Tong-Chuan He, and Rex C. Haydon: (2005) Gene Therapy for Spinal Fusion.  Spine Journal 5 (6 Suppl): S250-258. [PDF]

T.-C. He: (2005) Distinct osteogenic activity of BMPs and their orthopaedic applications.  Journal of Musculoskeletal & Neuronal Interactions  5(4): 363-366. [PDF]

Yejia Zhang, Zhen Li, Eugene J-M.A. Thonar, Howard S. An, Tong-Chuan He, Daniel Pietryla, and Frank M. Phillips: (2005) Transduced bovine articular chondrocytes affect the metabolism of co-cultured nucleus pulposus cells in vitro: Implications for chondrocyte transplantation into the intervertebral disc. Spine  30(23): 2601-7.  [PDF]

Rex C. Haydon and Frank M. Phillips: (2005) Primary Tumors of the Spine, in Cancer in the Spine: Handbook of Comprehensive Care, Eds. R. McLain, M. Markman, R. Bukowski, R., Macklis, and E. Benzel. Totowa, NJ: Humana Press.

Rex C. Haydon: (2005) Bone Sarcomas, in Cancer Medicine, Eds. C. Brown, B. Rini, P. Connell and M. Posner, pp304-313. Hamilton, ON: BC Decker, Inc.

Gurvinder S. Deol, Rex Haydon and Frank M. Phillips: (2005) Tumors of the Spine.  In Orthopaedic Knowledge Update, ed. A. Vaccaro, pp.587-598. Rosemont, IL: AAOS.

Jun Sun, Michael E. Hobert, Yingli Duan, Anjali S. Rao, Tong-Chuan He, Eugene B. Chang, James L. Madara: (2005) Crosstalk between NF-kappaB and beta-catenin pathways in bacterial-colonized intestinal epithelial cells.  American Journal of Physiology - Gastrointestinal and Liver Physiology   289(1): G129-37. [PDF]

P. Tao, J. Zhang, N. Tang, B.-Q. Zhang, T.-C. He, and A.-L. Huang: (2005) Potent and specific inhibition of SARS-CoV antigen expression by RNA interference. Chinese Medical Journal (Engl.)  118(9):714-719.

Jeffrey Luo, Daniel P. Mass, Craig S. Phillips, and Tong-Chuan He: (2005)  The Future of Flexor Tendon Surgery. Hand Clinic  21(2): 267-273.

Jeffrey Luo, Michael H. Sun, Quan Kang, Ying Peng, Wei Jiang, Hue H. Luu, Qing Luo, Jae Yoon Park, Yien Li, Rex C. Haydon, and Tong-Chuan He: (2005)  Gene Therapy for Bone Regeneration.  Current Gene Therapy  5(2): 167-179. [PDF]

Olaronke Akintola-Ogunremi, Qing Luo, Tong-Chuan He, and Hanlin L. Wang: (2005) Is Cytomegalovirus Associated with Human Colorectal Tumorigenesis?  American Journal of Clinical Pathology  123: 244-249. [PDF]

Vishal Mehta, Quan Kang, Jeffrey Luo, Tong-Chuan He, Rex C. Haydon, and Daniel P. Mass: (2005) Characterization of Adenovirus-mediated Gene Transfer in Rabbit Flexor Tendons.  Journal of Hand Surgery  30(1):136-141. [PDF]

Qing Luo*, Quan Kang*, Weike Si, Wei Jiang, Jong Kyung Park, Ying Peng, Xinmin Li, Hue H. Luu, Jeffrey Luo, Anthony G. Montag, Rex C. Haydon, and Tong-Chuan He: (2004) Connective Tissue Growth Factor (CTGF) is regulated by Wnt and BMP signaling in osteoblast differentiation of mesenchymal stem cells.  Journal of Biological Chemistry  279 (53): 55958-55968. (*contributed equally to this work) [PDF]

Hue H. Luu, Ruiwen Zhang, Rex C. Haydon, Elizabeth Rayburn, Quan Kang, Weike Si, Jong Kyung Park, Hui Wang, Ying Peng, Wei Jiang, and Tong-Chuan He: (2004) Wnt/beta-Catenin Signaling Pathway as Novel Cancer Drug Targets.  Current Cancer Drug Targets   4: 653-671. [PDF]

Quan Kang*, Michael H. Sun*, Hongwei Cheng*, Ying Peng, Anthony G. Montag, Andrea T. Deyrup, Wei Jiang, Hue H. Luu, Jan Paul Szatkowski, Pantila Vanichakarn, Jae Yoon Park, Jeffrey Luo, Yien Li, Rex C. Haydon, and Tong-Chuan He: (2004) Characterization of the distinct orthotopic bone forming activity of 14 BMPs using recombinant adenovirus-mediated gene delivery.  Gene Therapy   11 (17): 1312–1320. (*contributed equally to this work) [PDF]

Ying Peng*, Quan Kang*, Qing Luo, Wei Jiang, Weike Si, Bernard A. Liu, Hue H. Luu, Jong Kyung Park, Xinmin Li, Jeffrey Luo, Anthony G. Montag, Rex C. Haydon, and Tong-Chuan He: (2004) Id Helix-Loop-Helix Proteins Mediate BMP-induced Osteoblast Differentiation of Mesenchymal Stem Cells.  Journal of Biological Chemistry  279(31): 32941-32949. (*contributed equally to this work) [PDF]

Rex C. Haydon, Lan Zhou, and Tong-Chuan He: (2004)  Commentary: Tyrosine Kinase Inhibitor STI-571: The New Wonder Drug of Cancer Therapy?  Cancer Biology and Therapy  3(4): 393-394. [PDF]

Jae Yoon Park, Qing Luo, Wei Jiang, Quan Kang, Ying Peng, Catherine Strom, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He: (2004)  Dual Regulation of Gene Expression Mediated by Tetracycline and Cre Recombinase.  BioTechniques  39(3): 390-396. [PDF]

Ying Peng, Quan Kang, Hongwei Cheng, Xinmin Li, Michael H. Sun, Wei Jiang, Hue H. Luu, Jae Yoon Park, Rex C. Haydon, and Tong-Chuan He: (2003) Transcriptional Characterization of Bone Morphogenetic Proteins (BMPs)-Mediated Osteogenic Signaling.  Journal of Cellular Biochemistry  90: 1149-1165. [PDF]

N. Tang, A. L. Huang, B. Q. Zhang, G. Yan, and T.-C. He: (2003) Potent and specific inhibition of hepatitis B virus antigen expression by RNA interference.  Chinese Medical Journal (Engl.)  83(15):1309-1312.

Andrea T. Deyrup, Rex C. Haydon, Dezheng Huo, Akira Ishikawa, Terrance D. Peabody, Tong-Chuan He, and Anthony G. Montag: (2003) Myoid Differentiation And Prognosis In Adult Pleomorphic Sarcomas Of The Extremity: An Analysis Of 93 Cases.  Cancer  98 (4): 805-813. [PDF]

Hongwei Cheng, Wei Jiang, Frank M. Phillips, Rex C. Haydon, Ying Peng, Lan Zhou, Hue H. Luu, Naili An, Benjamin Breyer, Pantila Vanichakarn, Jan Paul Szatkowski, Jae Yoon Park, and Tong-Chuan He: (2003) Osteogenic Activity of the 14 Types of Human Bone Morphogenetic Proteins (BMPs).  Journal of Bone and Joint Surgery  85(8): 1544-1552. [PDF]

M.Q. Xiang, A.L. Huang, N. Tang, Y.J. Xiao, G. Yan, and T.-C. He: (2003) The expression of Recombinant adenovirus IkappaBalphaM in human hepatocarcinoma HepG(2) and it's inhibitive effect to the activity of NF-kappaB. Chinese Medical Journal (Engl.)  83(13): 1156-1160.

Michael H. Sun, Hongwei Cheng, Frank Phillips, Rex C. Haydon, and Tong-Chuan He: (2003) BMPs and Bone Regeneration.  Advances in Osteoporotic Fracture Management  2(3): 70-78.

Lan Zhou, Naili An, Rex C. Haydon, Qixin Zhou, Hongwei Cheng, Ying Peng, Wei Jiang, Pantila Vanichakarn, Jan Paul Szatkowski, Jae Yoon Park, Benjamin Breyer, and Tong-Chuan He: (2003) Tyrosine kinase inhibitor STI-571/Gleevec down-regulates the beta-catenin signaling activity.  Cancer Letters  193(2): 161-170. [PDF]

Ronjon Paul*, Rex C. Haydon*, Hongwei Cheng, Akira Ishikawa, Nikola Nenadovich, Wei Jiang, Lan Zhou, Benjamin Breyer, Tao Feng, Purnendu Gupta, Tong-Chuan He, and Frank Phillips: (2003) Potential use of Sox9 gene therapy for intervertebral degenerative disc diseases.  Spine   28(8): 755-763. (*contributed equally to this work) [PDF]

Lan Zhou, Naili An, Wei Jiang, Rex Haydon, Hongwei Cheng, Qixin Zhou, Benjamin Breyer, Tao Feng, and Tong-Chuan He:  (2002) Fluorescence-based Functional Assay for the Wnt/beta-Catenin Signaling Activity.  BioTechniques  33(5):1126-1135. [PDF]

Rex C. Haydon, Andrea Deyrup, Akira Ishikawa, Robert Heck, Wei Jiang, Lan Zhou, Tao Feng, David King, Hongwei Cheng, Benjamin Breyer, Terrance Peabody, Michael Simon, Anthony Montag, and Tong-Chuan He:  (2002) Cytoplasmic and/or Nuclear Accumulation of the beta-Catenin Protein is a Frequent Event in Human Osteosarcoma.  International Journal of Cancer.   102(4):338-342.  [PDF]

Tong-Chuan He. Association of COX-2 and PPARs in Carcinogenesis and Chemoprevention.  In COX-2 Blockade in Cancer Prevention and Therapy, Ed. R. E. Harris, Humana Press, Inc., New Jersey. pp225-244, 2002. [PDF]

Hanlin L. Wang, Julia Wang, Shu-Yuan Xiao, Rex Haydon, Debra Stoiber, Tong-Chuan He, Marc Bissonnette, and John Hart. (2002) Elevated protein expression of cyclin D1 and Fra-1, but decreased expression of c-Myc, in human colorectal adenocarcinomas overexpressing beta-catenin.   International Journal of Cancer  101:301-310. [PDF]

Tao Feng, Zhenggong Li, Wei Jiang, Benjamin Breyer, Lan Zhou, Hongwei Cheng, Rex C. Haydon, Akira Ishikawa, Mohanad A. Joudeh, and Tong-Chuan He: (2002) Increased efficiency of cloning large DNA fragments using a lower copy number plasmid.   BioTechniques  32(5): 992-998.  [PDF]

Rex C. Haydon, Lan Zhou, Tao Feng, Benjamin Breyer, Hongwei Cheng, Wei Jiang, Terrance Peabody, Anthony Montag, Michael A. Simon, and Tong-Chuan He: (2002) Nuclear receptor agonists as potential differentiation therapy agents for human osteosarcoma.  Clinical Cancer Research  8: 1288-1294. [PDF]

Benjamin Breyer, Wei Jiang, Hongwei Cheng, Rex Haydon, Lan Zhou, Tao Feng, Akira Ishikawa, and Tong-Chuan He: (2002) Development and Use of Viral Vectors for Gene Transfer: Lessons from Their Applications in Gene Therapy.  Applied Genomics and Proteomics. 1(1): 45-63.  [PDF]  

Wei Jiang*, Lan Zhou*, Benjamin Breyer*, Tao Feng, Hongwei Cheng, Rex Haydon, Akira Ishikawa, and Tong-Chuan He: (2001) Tetracycline-regulated gene expression mediated by a novel chimeric repressor that recruits histone deacetylases in mammalian cells. Journal of Biological Chemistry  276 (48): 45168-45174. (*contributed equally to this work) [PDF]

Tong-Chuan He.  Unit 12.4:  Adenoviral Vectors, in Current Protocols in Human Genetics   John Wiley & Sons, Inc., New York,  pp12.4.1-12.4.21, 2001. [PDF]

Benjamin Breyer, Wei Jiang, Hongwei Cheng, Lan Zhou, Ronjon Paul, Tao Feng, and Tong-Chuan He: (2001) Adenoviral vector-mediated gene transfer for human gene therapy.   Current Gene Therapy  1(2): 149-162. [PDF]

Ben H. Park, Benjamin Breyer, and Tong-Chuan He: (2001) Peroxisome proliferation-activated receptors: roles in tumorigenesis and chemoprevention in human tumor.   Current Opinion in Oncology  13:78-83. [PDF]

Some Earlier Publications (prior to 2000)

Ie-Ming Shih, Jian Yu, Tong-Chuan He, Bert Vogelstein, and Kenneth W. Kinzler (2000) The beta-catenin binding domain of Adenomatous polyposis Coli is sufficient for tumor suppression. Cancer Research  60:1671-1676. [PDF]

Luis T. da Costa, Tong-Chuan He, Jian Yu, Andrew B. Sparks, Patrice J. Morin, Kornelia Polyak, Steve Laken, Bert Vogelstein, and Kenneth W. Kinzler: (1999) Cdx2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling.   Oncogene, 18:5010-5014.  [PDF]

Tong-Chuan He, Timothy A. Chan, Bert Vogelstein, and Kenneth W. Kinzler: (1999) PPAR delta is an APC regulated target of nonsteroidal anti-inflammatory drugs.   Cell  99:335-345.  [PDF]

Tong-Chuan He, Andrew B. Sparks, Carlo Rago, Heiko Hermeking, Leigh Zawel, Luis T. da Costa, Patrice J. Morin, Bert Vogelstein, and Kenneth W. Kinzler: (1998) Identification of c-Myc as a target of the APC pathway.   Science,  281:1509-1512.  [PDF]

Kornelia Polyak, Todd Waldman, Tong-Chuan He, Kenneth W. Kinzler, and Bert Vogelstein: (1996) Genetic determinants of p53-induced apoptosis and growth arrest.    Genes & Development   10:1945-1952.

Luis  da Costa, Jin Jen, Tong-Chuan He, Timothy A Chan, Kenneth W Kinzler and Bert Vogelstein: (1996) Converting cancer genes into killer genes.   Proceedings of National Academy of Sciences USA   93:4192-4196  [PDF]

Ning Jiang, Tong-Chuan He,  Atsushi Miyajima, and Don M. Wojchowski: (1996) The box-1 domain of the EPO receptor specifies Jak2 and functions mitogenically within an IL2beta-receptor chimera.   Journal of Biological Chemistry  271:16472-16476.

Tong-Chuan He, Ning Jiang, Hongming Zhuang, Don M. Wojchowski: (1995) Erythropoietin-induced recruitment of Shc via a receptor phosphotyrosine-independent, Jak2-dependent pathway.   Journal of Biological Chemistry   270:11055-11061.

Hongming Zhuang, Zhutian Niu, Tong-Chuan He, Sunil V. Patel, Don M. Wojchowski: (1995) Erythropoietin-dependent inhibition of apoptosis is supported by carboxy-truncated receptor forms, and blocked by dominant negative forms of Jak2. Journal of Biological Chemistry   270:14500-14504.

Tong-Chuan He, Ning Jiang, Hongming Zhuang, Dawn E. Quelle, Don M.Wojchowski: (1994) The extended box-2 subdomain of erythropoietin receptor is nonessential for Jak2 activation yet critical for efficient mitogenesis in FDC-ER cells.   Journal of Biological Chemistry   269:18291-18294.

Hongming Zhuang, Sunil V. Patel, Tong-Chuan He, Zhutian Niu, Don M. Wojchowski: (1994) Dominant negative effects of a carboxy-truncated Jak2 mutant on EPO-induced proliferation and Jak2 activation.    Biochemical and Biophysical Research Communication  204(1):278-283.

Hongming Zhuang, Sunil V. Patel, Tong-Chuan He, Sherill K. Sonsteby, Zhutian Niu, Don M. Wojchowski: (1994) Inhibition of erythropoietin-induced mitogenesis by a kinase-deficient form of Jak2.   Journal of Biological Chemistry 269:21411-21414.

Tong-Chuan He, Hongming Zhuang, Ning Jiang, Michael D. Waterfield, Don M. Wojchowski: (1993) Association of the p85 regulatory subunit of phosphatidylinositol 3-kinase with an essential erythropoietin receptor subdomain.  Blood   82: 3530-3538.

Don M. Wojchowski and Tong-Chuan He: (1993) A concise review: Signal transduction in the erythropoietin receptor system.  Stem Cells  11:381-392.

Qian Li, Tong-Chuan He, Zheng-Tai  Wang: (1990) Establishment and comparison of three methods for GABA-transaminase activity measurement.  Acta Universitatis Scientiae Medicinae Chongqing   15: 70.

Tong-Chuan He and Zheng-Tai Wang: (1989).  Identification and characterization of a cerebral GABA-transaminase inhibitor in the livers from the acute liver failure mice.  Acta Universitatis Scientiae Medicinae Chongqing   14: 172.